The power to stop pain cold

iovera° – delivers immediate and sustained* non-opioid pain relief from postsurgical total knee arthroplasty (TKA)1 and chronic osteoarthritis (OA) of the knee2

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Clinical data summary

The clinical value of iovera has been established in two high unmet need settings of knee osteoarthritis and total knee arthroplasty, respectively.

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* Up to 14 days for postsurgical TKA pain and 90 days for chronic OA knee pain.


1. Dasa V, et al. Knee. 2016;23(3):523-528
2. Radnovich R, et al. Osteoarthritis Cartilage. 2017;25(8):1247-1256